リンク先には
Method
Antigenic peptides are determined using the method of Kolaskar and Tongaonkar (1990). Predictions are based on a table that reflects the occurrence of amino acid residues in experimentally known segmental epitopes. Segments are only reported if the have a minimum size of 8 residues. The reported accuracy of method is about 75%.
と書かれていますよね。
この情報が正しければ、
FEBS Lett. 1990 Dec 10;276(1-2):172-4.
A semi-empirical method for prediction of antigenic determinants on protein antigens.
Kolaskar AS, Tongaonkar PC.
に書かれている設計方法で設計していて、
約75%(169個中122個)がうまくいっていたのでは? |
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