ヒントを頂きありがとうございます。
cellの総説を検索したところ、
Among the four LC3 isoforms, LC3B is most widely used. Soon after synthesis, nascent LC3 is processed at its C terminus by Atg4 and becomes LC3-I, which has a glycine residue at the C-terminal end. LC3-I is subsequently conjugated with phosphatidylethanolamine (PE) to become LC3-II (LC3-PE) by a ubiquitination-like enzymatic reaction.
と記載がありましたので、
LC3B⇒LC3I⇒LC3IIと変換されていくものと理解できました。
ご教授頂きありがとうございましたm(_ _)m |
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